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The expected linear increase of yield with duration (at fixed flow rate) was observed until 8 (s), but then a dramatic increase in yield was observed

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The most common symptoms of acute nicotine poisoning are nausea, vomiting, headaches, and dizziness.[56] Approximately half of the children we interviewed in Indonesia in 2014 or 2015 reported experiencing at least one specific symptom consistent with acute nicotine poisoning while handling tobacco, including nausea, vomiting, headaches, and dizziness

Arnold and his crew of about 50 workers will do six pickings of the giant tobacco leaves

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Think of them as one-use packaging rather than a long-term holder