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Explainability task To better interpret the predictions of the classification models, we apply LIME 24 , an Explainable AI (xAI) framework 44 , to analyze the importance of features across different mental health classes

Mice that were euthanized before the studys end point were also excluded from analyses

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The intranasal treatment with DPL-loaded LNPs resulted in a considerably high concentration of medication in the brain, showing better brain target delivery (173)