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[52] In addition, substantial evidence implicates bile acids as an important factor in colon cancer

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The pathophysiological pattern common to these diseases may provide an explanation for the often poorly understood links between non-communicable diseases and disease comorbidities, like for instance CVDs and type 2 diabetes (Einarson et al., 2018), CVD, COPD and cancer (Buddeke et al., 2019), CVDs and osteoporosis (Farhat and Cauley, 2008), CVDs and AD (Stampfer, 2006), COPD and osteoporosis (Sarkar et al., 2015), CVDs and psoriasis (Hu and Cheng-Che, 2017), psoriasis and AD (Kim et al., 2020), and psoriasis with CVDs, cancers, type 2 diabetes and Crohns disease (Takeshita et al., 2017), to name but a few

As plaque and bacterial toxins accumulate, gum tissue becomes fragile