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The study, commissioned by the Department of Health, draws on the most recent data from the British Doctors Study, which began in 1951 and is considered one of the world's first major studies of the effects of smoking

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The impact of epidemiological changes on DALYs and deaths was even greater because of the implementation of superior healthcare and disease prevention strategies in these regions, which were significant in regions with a higher SDI and income ( Supplementary Table S2 , Figure 4 )