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[7][11] Common Side Effects: Nausea (which is the most common, affecting about 30% of users) Trouble sleeping or unusual, vivid dreams Constipation, gas, and vomiting [11] Rare but serious risks: Mental health symptoms, like mood swings, feeling depressed, or having thoughts of harming yourself (seek help right away if you feel like hurting yourself) Heart problems, especially in people with pre-existing conditions Serious allergic reactions (anaphylaxis), like swelling of the face, lips, or throat, or severe skin rashes, like Stevens-Johnson syndrome and erythema multiforme Sleepwalking, which sometimes leads to harmful behaviors Seizures, particularly in people with a history of seizures [11] Varenicline interactions Alcohol: Varenicline may increase the effects of alcohol, potentially causing unusual or aggressive behavior

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References [1] Gardner, Amanda (2011), Pack-a-day Smokers Declining, CNN, [2] Tobacco (2017), World Health Organization, [3] Fast Facts, Center for Disease Control and Prevention, access date: October 24, 2017

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Be open with your doctor about any marijuana use as it relates to your overall health, even though it may be a sensitive topic, because it will help to better understand how that might interfere with prescribed medications or trigger cardiovascular conditions or events, such as heart attacks and strokes