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In April 2022, the FDA announced a proposed product standard because it had the potential to significantly reduce disease and death and reduce youth experimentation and addiction as well as increase the number of smokers who quit

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In order to investigate this, rodent models of allergic asthma were co-exposed to CS and endpoints of the Late Asthmatic Response (LAR), Airway Hyper-Responsivity (AHR) and airway cellular burden were assessed