definition of smoking cigarettes What Are Cigarettes? Smoking | PPT

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We think that while it is clear that different endpoints may yield quite different results, the human MOE for cannabis based on the endpoint psychotropic effects can be seen as general validation of the MOE concept, because the resulting values below 1 are expected as the psychotropic effect is the desired endpoint (and hence the psychotropic threshold dose is exceeded by drug users)

Those low yield brands were designed to show lower tar and nicotine yields on the federal trade Commission (FTC) smoking machine, but the machine did not mimic how humans actually used low yield cigarettes