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Cross the Sint-Michielsbrug, the stone bridge built in 1909, and along Catalonistraaat which will take you past the church of St Nicholas and on to the Belfort

Go towards the Dock and pick up the Gas Cannister

Itll never look as cool as smoking cigarettes

The trial team also gratefully acknowledges the following for their contributions: Sadie Kelly, Darren Connor, David Judge on behalf of University of Oxford PC-CTU for their guidance and input on data management, programming, risk assessment and trial monitoring

KEY STATISTICS MAJOR CHALLENGES FOR SA INDUSTRY To remain relevant, growing and competitive in the long term, the industry will have to deal with: Tight regulation by Government Increasing excise duties Growth in the illegal trade Declining legal local market Proper dialogue between DOH, other stakeholders and industry is non-existent

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