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The associations between all variables are presented as odds ratios (ORs) and 95% confidence intervals (CIs)

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This association remained statistically significant following adjustments for potential confounding variables

The popular JUUL devices were originally introduced in 2015 with a 5% nicotine salt pod, prompting JUUL competitors to begin offering nicotine salt concentrations as high as 7% in what has been called a nicotine arms race. High nicotine products make up bulk of e-cigarette market To gauge change in nicotine levels, researchers examined e-cigarette retail sales data from January 2017-March 2022 in brick-and-mortar retailers across the continental U.S

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