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This is the most restricted category of controlled substances, which the agency defines as drugs with no currently accepted medical use and a high potential for abuse. However, some states, like Indiana, have passed laws legalizing the substance, indicating that despite mixed evidence as to the compounds effects and federal guidelines that legislate against it, CBD is here to stay.

The actual amount of nicotine absorbed during smoking can be lower due to factors such as incomplete combustion and filtration by the cigarette filter

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