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Oxidative stress and oxidative stress-induced DNA damage caused by smoking can activate NF-B, MAPKS, and mTOR pathway [21]

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Another key player

Maybe its just contractors working on the place, taking a smoke break, I reasoned

Therefore, one of the most effective ways a person can reduce his or her risk of skin cancer is by practicing sun-safe habits and not using UV indoor tanning devices (see sidebar on Ways to Protect Your Skin)