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Identification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism

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11 Smokers are also half as likely to respond to preoperative chemotherapy, more likely to have their bladder cancer return after surgery, and more likely to die of cancer

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Additionally, the authors note that PMIs premarket application did not adequately examine the health consequences of dual product use, consider potential youth attraction and use of the product, or evidence that consumers recognize the perceived addiction risk of the product