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If medications fail, your doctor might recommend an electronic nicotine delivery system (ENDS), such as e-cigarettes, as an alternative treatment

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However, another study on water-soluble and hexane-soluble extracts showed that the latter significantly induce MMP-1 gene expression 36 , suggesting that the insoluble compounds of cigarette smoke could also induce deleterious effects

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However, it's important to note that medication use should be determined by a healthcare professional based on an individual's specific needs