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Nicotine Level: Strong

This is bound to be a persistent problem, as longitudinal studies that determined smoking onset during adolescence are unlikely to follow participants into late adulthood, when HRQOL determinations were made

However, other observational studies showed the oppositee-cigarettes were not associated with increased combustible cigarette smoking cessation in both youth and adult populations 35,36

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Smith's research found that CBD reduced blood cotinine levels (a nicotine metabolite) by 27% without affecting nicotine levels themselves