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Shisha smoking, while often perceived as less harmful due to the water filtration, exposes users to high levels of toxic substances during prolonged sessions

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Though legal in most countries, the substance can elicit psychoactive effects and should only be used after speaking with a healthcare professional.

Immunity 36:933946 Arnoult D, Soares F, Tattoli I, Castanier C, Philpott DJ, Girardin SE (2009) An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix