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This diverse community, which includes bacteria, viruses, fungi, and archaea, has co-evolved with humans over millennia, forming complex ecosystems that are essential for processes such as nutrient absorption, immune modulation, and pathogen defense [24,25,26]

Xiao, L., Parascandola, M., Wang, C

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Having a cold sore does mean that you are carrying the herpes simplex virus (HSV-1)

Esophageal Muscles : As with the lower esophageal sphincter, nicotine can also relax the smooth muscle that lines the entire length of the esophagus

In contrast, other studies reported that smoking reduces serum uric acid levels and has a protective effect against the risk of gout 7-10