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Most tobacco products, including e cigarettes, contain nicotine, a chemical that can harm the heart, brain and whole body. As with other addictive products, using a nicotine product builds tolerance, leading to more 5 Most Addictive Drugs of Abuse in 2026: Evidence Based Rankings Global Women's Network Quit Smoking Fact Sheets Yale Medicine 2024 01 Your drug questions answered Wits University What are the Most Addictive Drugs? Castle Craig The 5 Most Addictive Drugs Footprints to Recovery Leading Drug & Alcohol Treatment Programs
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