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If your small company has been flying under the radar thus far, you might find yourself with a lot of paperwork and registration fees to catch up on

Since the products are relatively new to Canada, governments at all levels still need to address the sale and use of the products, whether its approving the ingredients in e-liquids, developing by-laws to prohibit the use of e-cigarettes in public places, or banning the marketing and sale of the products to minors.

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These findings are published in JAMA Network Open

The center has an annual budget of more than $450 million, much of it funded by the industry, and more than 365 employees, about 115 of whom work on the application reviews