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The carcinogens present in tobacco smoke, such as benzene, formaldehyde, and polycyclic aromatic hydrocarbons, damage the DNA in lung cells, leading to the uncontrolled growth of cancer cells

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COX-2 produces prostaglandin-E2 (PGE 2 ), which promotes angiogenesis and tumor growth (Sahu et al

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Unfortunately, the latter didn't happen