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Notably, several interventions linked to one or more of these mechanisms have been or are now being explored in PD, including several small-molecule compounds, and even controlled exposure to nicotine, low-dose carbon monoxide, and moderate hypoxia 26,27,28,29

While these results suggest that nicotine products were not a primary cause of EVALI, a potential role for nicotine products cannot be entirely ruled out given the relatively small number of exclusive nicotine users included in the analysis

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The research team then looked at whether newborns needed ventilation following delivery or treatment for lung problems, blood infections, seizures or serious neurological problems