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A randomized, placebo-controlled trial tested the effect of Nabiximols (which is a new cannabinoid drug) as add-on therapy on opioid-refractory cancer patients

Homogenous refers to the uniformity of the color and the texture of the leukoplakic lesion while non-homogenous leukoplakia may have a red-white appearance or may have a uniform white appearance with an irregular texture manifesting with nodules wart-like projections and corrugations

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Despite the dominance of filtered cigarettes, unfiltered options still have a loyal following