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It is well documented that cigarette smoke can induce cytochrome P450 (CYP) isoenzymes, specifically CYP1A1, CYP1A2, and CYP2E1

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Accordingly, the criteria (and screening tools developed using such criteria) that have been proposed to diagnose an addiction to the mobile phone were directly transposed from those classifying and diagnosing other addictive behaviors, i.e., the criteria for substance use and pathological gambling depicted in the fourth revised edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) in the case of the first published studies on PMPU [6, 17]

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