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While it is now evident that pipe smoking is less harmful than cigarette smoking, it must never be forgotten that improper usesuch as smoking more than five bowls per day, inhaling the smoke, or misusing the pipecan make the risks equal or even greater than those of cigarettes

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Another study observed significant interactive effects of in utero exposure to smoking and either DAT1 or DRD4 polymorphisms in predicting combined type ADHD

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