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Blood vessels tighten, reducing oxygen flow and forcing the heart to work harder to push blood through narrower pathways. Over time, this repeated strain contributes to tachycardia, an abnormally high heart rate that can lead to arrhythmias or irregular heartbeats

Acknowledgments The authors acknowledge Lance Barnes, Stacy Minnix, Ellen Mitchell RN, Chris Cryan, and Haleh Nadim for their contributions to recruitment, data collection, data management, and laboratory analysis

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