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The inhibition of ABTS + formation by antioxidants in the samples were expressed as Trolox equivalents, determined at 740 mm using a calibration curve plotted with different amounts of Trolox (Sigma Aldrich) ( Glutathione (GSH) Levels The level of GSH was determined in samples of serum and peritoneal lavage fluid of septic mice at 12 and 24 h post CLP induction using Ellman's reagent ( In vitro Studies Peripheral Blood Mononuclear Cells (PBMC) Isolation and in vitro Stimulation PBMC of healthy volunteers who were abstainers of alcohol and tobacco (both sexes, ages 20 to 45 years) were isolated from blood using Ficoll (Sigma-Aldrich)

Serum antioxidant capacity in the groups receiving N-acetylcysteine was significantly increased compared to the socially isolated stress group receiving normal saline (Fig

In traditional system of medicines, bioactive ingredients of Shatavari, Asparagus racemosus (hereafter Shatavari) are well-known phytoadaptogens and their therapeutic potential have already been documented in Indian and British Pharmacopeias[28]

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The binding affinity of the alkaloids for the 5-HT1A receptor is dramatically reduced when their orientation is switched from R to S (mitragynine/speciociliatine)