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Multivariable analysis with time-dependent exposure and confounders After considering time-dependent exposure and confounders identified by the DAG (Figure 2), we used MSM with the GEE approach, adjusting for age at initiation of cigarette-use, sex (time-independent confounders), income, alcohol consumption, and motivation to quit smoking (time-dependent confounders) through IPW to balance confounders across each type of cigarette-use

Available online at: Summary Keywords ECIG, E-liquid, vaping, smoking, aerosol, trace metals Citation Palazzolo DL, Crow AP, Nelson JM and Johnson RA (2017) Trace Metals Derived from Electronic Cigarette (ECIG) Generated Aerosol: Potential Problem of ECIG Devices That Contain Nickel

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Caffeine, however, is also addictive and should be used only when necessary given its health implications