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They feared future conflict with the new American state to the south and saw the numerous First Nations warriors as essential to their colony's defence

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While additional research is required to fully understand the exact relationship between smoking and infection from SARS-CoV-2, it has been well-documented that smoking is a major risk factor for the incidence of respiratory infection, including other coronaviruses such as MERS, as well as for the severity of disease progression [ 75 , 76 ]