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The serum cotinine concentration in E-cig exposed mice, which was 267 ng/ml, is comparable to those levels found in both cigarette smokers and E-cig users, which often exceed 300 ng/ml

The problem was compounded by the fact that adjacent states did not tax cigars, so Michigan residents who lived near the border often purchased them in neighboring states, sometimes sidestepping Michigan's tobacco products use tax during the shopping trips

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