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The symptoms can include: flu-like symptoms nausea extreme tiredness itchy skin stomach pain jaundice, where the whites of your eyes turn yellow, your skin may take on a yellowish colour, and your urine is dark and your faeces (poo) are pale mental confusion (often called brain fog) and depression these are specific to the C strain of hepatitis

Biological intermediates as transducers of systemic effects In addition to exposure, the development of biological intermediates also needs special attention (145, 153, 163168)

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The model was later revisited by Thun et al

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