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For more advanced or persistent cases, especially when prior treatments like chemoradiation fail, a more extensive surgical option known as abdominoperineal resection (APR) may be necessary

Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2012 [accessed 2016 Apr 14]

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38A Croc, but not gator : SHOE Crocs are foam clogs that were originally designed as shoes to be worn at health spas

We remind consumers that tobacco contains nicotine and nicotine is an addictive chemical

Taking a pinch of the Skoal mint in her lip, she grimaces