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This process can be affected by nicotine since it speeds up transportation time leading to diarrhea or frequent passing out of watery stools, but on the other hand, some people could experience the opposite effect, where bowel spasms due to the use of nicotine, thereby causing constipation

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"But I feel annoyed when they refer to him as the smoking kid

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Most of these areas are innervated by dopamine inputs, which suggests that the activation of mesolimbic and mesocortical dopaminergic systems may allow for interactions between nicotine and THC or cannabinoids

Aging ratio is the ratio of predicted age to observed chronological age