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A data set for the IQOS tobacco heating system, a heated tobacco product manufactured by Philip Morris International, indicated that out of 24 biomarkers of potential harm, there was no statistical differences between people using the IQOS and tobacco cigarettes in 23 of 24 biomarkers (6)

European Respiratory Journal 2009;33(4):75462

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In fact, much of the progress in tobacco control, most notably in protecting the public from exposure to others smoke by the passage of clean indoor air laws, occurred in the 1970s, 1980s, and 1990slong before the creation in 2014 of 14 mostly university-based centers of excellence in tobacco regulatory science, each given $20 million by the FDA