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tabacum has a large complex genome which is allotetraploid, meaning it comprises four sets of chromosomes from two different species (as opposed to most animals which inherit their chromosomes from two parents of the same species)

B., Xingyan Wang, Fang Chen, Seon Kyeong Jang, Mengzhen Liu, Chen Wang, Shuang Gao et al

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After going to a doctor and having a biopsy done, he got the bad news that he had a very aggressive form of cancer that directly resulted from his tobacco use

Your local fire marshall will let you know

He experienced trench warfare and wrote about the wretchedness of lice on the battlefield, which kept him and his friends up all night every night