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There is always the possibility of uptake among tobacco-naive individuals (including youth), former tobacco users, or current smokers interested in using IQOS for reasons that prolong rather than stop smoking behaviors (e.g., use in settings where cigarettes are prohibited), any of which would be a negative public health development

Ophthalmology 121 , 14351444 (2014)

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When performing healings, shamans often blow tobacco smoke onto the ill person to free him or her of disease spirits or to protect the patient from them

2020 Note: The estimated numbers of people with substance use disorders are not mutually exclusive because people could have use disorders for more than one substance