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Tobacco Use and Cardiovascular Disease Infographic Details World No Tobacco Day Tobacco Use and Cardiovascular Disease Over 7 Million people die from tobacco use each year worldwide, including 890,000 from exposure to secondhand smoke Tobacco smoking and breathing in secondhand smoke can cause cardiovascular disease including: Heart Disease Stroke Tobacco use is a major cause of cardiovascular disease Tobacco use is responsible for 10% of all cardiovascular disease deaths worldwide Implementation of the World Health Organization MPOWER demand reducing measures can reduce tobacco use and help protect people from secondhand smoke

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On the other hand, oxidative stress interferes with nitric oxide synthase by inhibiting the Nuclear Factor erythroid 2-Related Factor 2 (Nrf2) pathway and upregulating asymmetric dimethylarginine content

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