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Ongoing studies in our group, utilizing non-invasive imaging of the tumor reductive state, circulating biomarkers of Nrf2 hyperactivation and spatial transcriptomic analysis of primary and recurrent HNSCC tumors are attempting to define the clinical window in which activation of this pathway is expected to generate a maximal deleterious effect on both conventional and ICI-based treatment efficacy

persuade: To influence someone to take a course of action or embrace a point-of-view by means of argument, reasoning or appeal

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