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Nigella sativa Linn (Black cumin or black seed/ ) Nigella sativa can inhibit clot formation and enhance fibrinolysis, suggesting potential anticoagulant effects, it can also prolong prothrombin time (PT), a measure of blood clotting time, the anticoagulant activity is attributed to the ability of Nigella sativa to inhibit the activity of coagulation factors like factor VII, X, V, prothrombin (II), and fibrinogen in the extrinsic coagulation pathway and thymoquinone, a major constituent of Nigella sativa, has been linked to these anticoagulant properties