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People in long-term NHS care are much more likely to smoke and typically have worse physical health too, and about 28m is spent on additional drug costs for their treatment

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Furthermore, PG and VG do not cross the airway membranes and, when inhaled in large amounts, can induce hyperosmotic stress which may further induce both proinflammatory responses as well as cell stress responses [64], [65]

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For women who undergo surgical menopause (removal of their ovaries before menopause), hot flashes often begin right after surgery