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Medicine and Health Although physicians had raised concerns about the health hazards of smoking since the 1800s, from the 1920s to the 1940s the number of reports in medical journals implicating cigarette smoking as a cause of cancer (for example, Lombard and Doering New England Journal of Medicine 1928;198:481-7) and premature death (for example, Pearl in Science 1938;87:216-7) rose steadily

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