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Kreteks, a cigarette containing tobacco mixed with cloves, is produced and consumed predominantly in Indonesia

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Bibcode:2018PLoSO..1394145Z

The cigarette companies continue to send Umphrey and the group about $120 million annually, which will end when the $3.3 billion award is met

While this study has made initial strides in identifying key microbial taxa and their correlations with metabolite dynamics through multi-omics approaches, it further generates a novel testable hypothesis: that the dynamic co-occurrence of Staphylococcus , Ascomycota and Penicillium between T1 and T2 stages establishes a synergistic metabolic network crucial for the degradation of macromolecules (e.g., starch, nicotine) and the concurrent synthesis of key aroma compounds

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