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A comparison of mainstream and sidestream cannabis and tobacco cigarette smoke, Chemical Research in Toxicology (2008)

The rate at which nicotine leaves the system is affected by: how much nicotine a person uses and how often how long a person has been using tobacco products the persons overall genetics, health, and age Research has not yet determined whether vaping or smoking traditional cigarettes affects how rapidly the body breaks down nicotine.

Thanks to the use of cigarette filters, a large amount of harmful substances such as condensate and gases can be filtered out of the cigarette smoke

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In particular, a However, a 2017 reviewconcluded that in-vitro conditions dont represent the actual conditions in a human stomach, where a similar transformation doesnt appear to occur