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Unlike when smoking tobacco, you can continue to enjoy the flavors and act of vaping without consuming nicotine

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After nicotine is absorbed into the bloodstream through smoking or other means, it undergoes metabolism primarily in the liver, where it is converted into cotinine

Quantitation of serum nicotine, cotinine, adrenalin, and -endorphin via Ultra-fast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS) Nicotine and cotinine This study used a validated SHIMADZU UFLC-MS/MS system (Waters Corporation, Milford, MA, USA) to determine the concentration of nicotine and cotinine in rat serum

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