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Nicotine Makes Me Feel Sick: How Nicotine's Chemicals Can Cause Discomfort Cigarette smoke contains thousands of chemicals, many of which are toxic and harmful to the human body. Here's a detailed breakdown of some of the most dangerous constituents and their effects: 1. Sometimes when people vape for the first time they can feel quite unwell and, in some cases, they can actually be sick. This is due to the nicotine they're ingesting and is Can Hookah Make You Sick? Learn the Causes Smoking: Effects, Risks, Diseases, Quitting & Solutions File:Tobacco diagram.png Wikimedia Commons

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