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When rats were exposed via inhalation to e-cigarette aerosols (11 cycles/day, 5 days/week for 4 weeks), a statistically significant fourfold increase in the formation of 8-hydroxy-deoxy-guanosine was found in the lungs, along with other evidence of oxidative stress in these animals

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We used Cox proportional hazards models adjusted for age, race/ethnicity, marital status, education, income, health status, body mass index, and region to estimate hazard ratios (HRs

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