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Querying the phenome-wide association results of this variant in a public repository of genetic association results hosted by the Japan biobank 21 , we found that the top association of the pLOF variant (which was the only significant association across the phenome after adjusting for multiple testing) was cig per day, with an effect size comparable to that of p.Glu284Gly in the MCPS cohort (beta = 0.19

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Despite our knowledge of the multitude of cancer causing agents and toxins in tobacco, people still use it

5 enhances pulmonary oxidative stress ( 2

Less collagen production in smokers, Surgery, 1998, vol