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This happens when there are just too many of these types of dangerous molecules and the scavenger receptor system becomes overwhelmed and cannot get rid of them all. So the ROS molecules, the oxidants, are left free to go and bind to everything any type of molecule they can find, including our DNA, Dr Carol explains

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The results are, therefore, consistent with SBS16, DBS4 and ID16, all being generated by the same underlying alcohol-related mutational process, and with the mutagenicity of this process being increased with co-exposure to tobacco smoke