MaP555-Alkyne (cell-permeable fluorogenic dye) Size:1mg Contains an E3 ligase ligand

Contains an E3 ligase ligand substituted with piperidine

Product Name Thalidomide-5'-propargyl-OH Synonyms CAS Number 1216805-32-1 Related CAS Molecular Formula C16H12N2O5 Molecular Weight 312

Product Name Thalidomide-5'-piperidine-C1-alcohol Synonyms CAS Number 2229717-49-9 Related CAS Molecular Formula C19H21N3O5 Molecular Weight 371

Excitation maximum = 500 nm

408 SMILES OCCN1CCN(CC1)C1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

MaP555-Alkyne (cell-permeable fluorogenic dye) Size:1mg Contains an E3 ligase ligandMaP555 Alkyne is is a fluorogenic probe. MaP555 is a small molecule fluorogenic probe with excellent cell permeability. It is converted from 6 carboxytetramethylrhodamine (6 TAMRA) and has similar spectroscopic properties of 6 TAMRA. MaP555 has an acyl sulfamide structure which favors the spirolactam form, thus has excellent cell permeability. When the probe binds to its cellular targets, MaP555 mainly exists in the fluorescent zwitterion form. The