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Though studies are limited, evidence suggests that the chemicals in e-cigarettes can create conditions that promote breakouts, especially if you're already prone to acne

Arch Gen Psychiatry 1974

In the United States, an alternative emphasis has been to make cigarettes less likely to ignite (Howland & Hingson 1987

Medications such as nicotine replacement therapy, bupropion, and varenicline can also be used to manage withdrawal symptoms and reduce the urge to smoke