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Class II variants also have severe enzyme deficiency (less than 10% of normal), but there is usually only intermittent hemolysis

Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking

Pharmacognostical review of Urtica dioica L

Minimally invasive complete response assessment of the breast after neoadjuvant systemic therapy for early breast cancer (MICRA trial): interim analysis of a multicenter observational cohort study

Overall, these classes of derivatives have been designed to be more readily absorbed and retained in the body, thereby increasing their effectiveness in reaching and acting on target tissues, as well as the need for smaller doses sufficient to achieve the desired therapeutic effect [867, 868]

[PMC free article: PMC5604696] [PubMed: 28918406] [CrossRef] 185