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Description

IRP: iron regulatory protein

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Bugai, A

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Gomez D, Liao KP, Swisher SG , Blumenschein G, Erasmus J, Buchholz TA, Giordano SH, Smith B

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Efferocytosis of apoptotic neutrophils reprogrammed macrophage mitochondrial metabolism through mieloperoxidase-dependent UCP2, which increases proton conductance in the inner mitochondrial membrane, thereby impairing reactive oxygen species (mtROS) production in response to bacteria

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In the next section, studies performed to evaluate the effect of HMOX1 modulation in IBD will be discussed

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